By Marisa R. Nucci, Esther Oliva
This new identify within the Foundations in Diagnostic Pathology sequence bargains today's so much crucial gynecologic pathology information in a compact, high-yield structure! for every pathologic entity tested, you'll locate discussions of scientific positive aspects, pathologic gains (gross and microscopic), in addition to ancillary stories, differential prognosis, and prognostic and healing issues. The text's pragmatic, well-organized approach-complemented through considerable full-color, high quality illustrations and at-a-glance tables-makes it effortless so that you can entry the knowledge you must quick and effectively determine pathology specimens. the result's a pragmatic, cheap source for research and evaluate in addition to for daily medical reference.
- Covers either neoplastic and non-neoplastic stipulations of the feminine reproductive tract to equip you to satisfy quite a lot of diagnostic challenges.
- Uses a constant, undemanding structure to discover each one entity's scientific beneficial properties . pathologic gains (gross and microscopic) . ancillary experiences . differential diagnoses . and prognostic and healing concerns, making it effortless to find particular details on a specific entity.
- Features considerable containers and tables all through, bettering the presentation and accessibility of the material.
- Offers hundreds of thousands of full-color, top quality illustrations that display the main positive factors of a wide selection of pathologic lesions to facilitate larger accuracy in id of specimens.
The Foundations in Diagnostic Pathology sequence solutions the decision for clean, cheap, and easy-to-use suggestions. each one region-specific quantity presents the entire so much crucial info at the pathologic entities encountered in perform.
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Extra info for Gynecologic Pathology (Foundations in Diagnostic Pathology Series)
Approximately 10–15% of the lesions are hyperpigmented. Well-differentiated/simplex VIN can be seen as focal discoloration, ill-deﬁned white plaque(s), or discrete elevated nodules, but they are typically less bulky than typical VIN lesions. Both typical and well-differentiated VIN are frequently multifocal. Bleeding and infection may occur due to scratching, with secondary scar formation. Clinically, a high degree of suspicion is necessary to avoid misdiagnosis since the lesions may be subtle.
Genes Chromosomes Cancer 2001;32:172–176. Steeper TA, Rosai J. Aggressive angiomyxoma of the female pelvis and perineum. Report of nine cases of a distinctive type of gynecologic soft-tissue neoplasm. Am J Surg Pathol 1983;7:463–475. Tsang WY, Chan JK, Lee KC, et al. Aggressive angiomyxoma. A report of four cases occurring in men. Am J Surg Pathol 1992;16:1059–1065. Angiomyoﬁbroblastoma Fletcher CD, Tsang WY, Fisher C, et al. Angiomyoﬁbroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma.
23 Psoriasis. The suprapapillary plates are thinned and contain dilated capillaries, often in immediate apposition to the overlying epidermis. CHAPTER 1 23 Inﬂammatory Diseases of the Vulva PSORIASIS – PATHOLOGIC FEATURES Microscopic Findings Early Lesion ៉ Epidermal spongiosis ៉ Papillary dermal vascular congestion and edema ៉ Sparse perivascular dermatitis LICHEN SIMPLEX CHRONICUS – FACT SHEET Deﬁnition ៉ Idiopathic condition in which scaly plaques are formed in response to repetitive rubbing of affected sites Incidence ៉ Common Advanced Lesion ៉ Regular acanthosis with increased basal mitotic activity ៉ Mounds of neutrophil-rich parakeratosis ៉ Hypogranulosis Mature Lesion ៉ Marked regular psoriasiform epidermal hyperplasia with thinned suprapapillary plates ៉ Conﬂuent neutrophil-rich parakeratosis, “Munroe microabscesses”, and “spongiform pustules of Kogoj” Morbidity ៉ Cosmetic ៉ Superinfection if abraded and ulcerated lesions Gender, Race, and Age Distribution ៉ More common in women than men ៉ No racial predilection ៉ Peak incidence between 30 and 50 years ៉ Papillary dermal vascular ectasia ៉ Lymphocytic-rich perivascular dermatitis Clinical Features Differential Diagnosis ៉ Hyperpigmented scaly plaques at sites of repetitive rubbing ៉ Perianal and genital regions, posterior neck, forearms, and ៉ Lichen simplex chronicus ៉ Seborrheic dermatitis ៉ Dermatophytosis and candidiasis pretibial areas are anatomic sites of predilection Prognosis and Treatment ៉ Cessation of the itch–scratch cycle ៉ Emollients, topical steroids, and barrier occlusion ៉ Behavior modiﬁcation and psychopharmacologic agents may be beneﬁcial in select patients DIFFERENTIAL DIAGNOSIS Late-stage lesions of LSC (see below) can usually be differentiated from psoriasis by the presence of thicker suprapapillary plates, hypergranulosis, and the presence of thickened vertically oriented collagen bundles within the papillary dermis.
Gynecologic Pathology (Foundations in Diagnostic Pathology Series) by Marisa R. Nucci, Esther Oliva