By Dennis H. Wright, Bruce J. Addis, Anthony S.-Y. Leong
"Diagnostic Lymph Node Pathology" is a finished and generously illustrated consultant, making it the fitting useful reference publication. The overseas group of very popular haematopathologists write in an authoritative and obtainable type with an emphasis on morphological assessment in addition to immunohistochemistry. The ebook basically and logically offers the standards for differential prognosis with illustrations of either classical and no more recognized positive factors of every affliction strategy. it will end up to be an important consultant for all surgical pathologists and haematopathologists excited by reading lymph node biopsies and may be a useful studying textual content for histopathologists in education.
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Additional resources for Diagnostic Lymph Node Pathology (Hodder Arnold Publication)
Occasionally, atypical cells and cells resembling Hodgkin/Reed–Sternberg cells are seen. However, this is a feature more frequently encountered in tonsils than in lymph nodes. OTHER VIRAL LYMPHADENOPATHIES Other common viruses that cause lymphadenitis include cytomegalovirus, Herpes simplex, varicella– Herpes zoster and vaccinia; however, such cases are rarely biopsied. Although there may be some element of follicular hyperplasia, such nodes usually show a predominant pattern of paracortical hyperplasia.
69 Lepromatous leprosy. Stain for acid-fast bacilli shows large numbers of leprosy bacilli in lepra cells. 70 Bacille Calmette–Guérin (BCG)-infected lymph node from an immunosuppressed patient showing an area of necrosis surrounded by plump histiocytes. 71 Bacille Calmette–Guérin (BCG)-infected lymph node from an immunosuppressed patient stained by the Ziehl–Neelsen method. Large numbers of acid-fast bacilli fill the plump histiocytes. 72 Mycobacterium avium intracellulare infection in an immunosuppressed patient.
High-power view showing histiocyte and giant cell reaction to the contrast medium. The sinuses of the lymph node are filled with foamy histiocytes surrounding lipid vacuoles. 53 Whipple disease. Periodic acid Schiff stained section showing large numbers of bacilli in foamy histiocytes. The sinuses shown are filled with a meshwork of endothelial cell-lined vascular spaces. GRANULOMATOUS LYMPHADENITIS These are lymphadenopathies that are characterized by the presence of granulomas or localized aggregates of histiocytes as the most prominent feature.
Diagnostic Lymph Node Pathology (Hodder Arnold Publication) by Dennis H. Wright, Bruce J. Addis, Anthony S.-Y. Leong