By W. J. Hayes Jr., S. W. Simmons, E. F. Knipling (auth.), Paul Müller, S. W. Simmons (eds.)
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Additional info for DDT: The Insecticide Dichlorodiphenyltrichloroethane and Its Significance / Das Insektizid Dichlordiphenyltrichloräthan und Seine Bedeutung: Human and Veterinary Medicine
253]. I ntermuscular E xposure PLUVINAGE and HEATH  reported that cats withstood two to nme intermuscular doses of DDT in oil, totaling 135 to 665 mgjkg, before the onset of symptoms. It was not possible to produce chronically poisoned animals; the cats either developed slight transient illness and recovered, or developed progressive illness and died. 41 4. USE OF DDT FOR THE CONTROL OF UNDESIRABLE VERTEERATES Since DDT is toxic to mammals generally, it has occurred to several workers that the compound might have a practical use as a rodenticide.
432]). Focal necrosis (NELSON et al. ) or hemorrhage (CAMERON ; CAMERON and BURGESS ; ZEIN-EL-DINE ) of the adrenal cortex has occasionally been seen. Focal necrosis of the gall bladder of heavily dosed rabbits has been reported (NELSON et al. ). Significant changes in the testis (NELSON et al. ; DIAZ- ]IMENEZ ), bone marrow (NELSON et al. ), bone (NELSON et al. ) and pancreas (NELSON et al. ), have not been found. Effect of Repeated Doses Neuromuscular System Some early authors (LILLIE and SMITH ; NEAL et al.
680] MARSDEN and BIRD  TELFaRD and GUTHRIE  RUBIN et al. ,p.. § 0 ~ "1j "' 8"' 8"' Turkey Chicken Chicken4) Species 650-710 mkd 1 1,000 mkd 5,000 ppm 400 mkd 2,500 ppm 300 mkd - 3,900 6,000 - - - 483 - 1,350 11,000 - - - - - 1,610 - - - - - - Fatal to all animals 760 Fatal to one animal Minimum - 4,260 - 2,000 - 7,250 - - 12,000 1,1401) - 6 4 18 1 18 - 5 10 - 8 6 10 10 Nurober of Maxianimals mum tolerated in test Total dosage (mg/kg) 17 100 100 0 100 0 0 100 0 50 67 100 100 % Mortality ----- ------------ -- ---- ---- -- -- _j W ASICKY and UNTI [648) SPICER et al.
DDT: The Insecticide Dichlorodiphenyltrichloroethane and Its Significance / Das Insektizid Dichlordiphenyltrichloräthan und Seine Bedeutung: Human and Veterinary Medicine by W. J. Hayes Jr., S. W. Simmons, E. F. Knipling (auth.), Paul Müller, S. W. Simmons (eds.)