By Paul Van de Heyning, Andrea Kleine Punte
Electrical acoustic stimulation (EAS) combines electrical stimulation within the mid to high-frequency areas with acoustic stimulation within the low-frequency variety with the purpose to maintain residual low-frequency listening to after cochlear implantation, which jointly fairly improves speech realizing, pitch discrimination and track appreciation. during this quantity, the main skilled medical teams percentage their realizing of using EAS in adults and youngsters. It bargains an in-depth audiological research relating to making a choice on, getting ready and rehabilitating EAS sufferers. themes equivalent to useless sector evaluate, psychophysics of low-frequency listening to, electric-acoustic interplay, speech algorithms, song belief, in addition to becoming and the patient's reputation are mentioned. Introductory chapters - illustrated with unprecedented color photos - on cochlear neural reserves, molecular biology and high-technological electrode improvement specialize in the elemental medical EAS examine. each ENT expert, audiologist, speech therapist and scientist attracted to internal ear pathology, inquisitive about cochlear implantation or facing the remedy or surgical procedure of the interior ear will enjoy the insights and reviews of the world's major specialists who contributed to this ebook.
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Extra resources for Cochlear Implants and Hearing Preservation (Advances in Oto-Rhino-Laryngology, Vol. 67)
38 Furthermore, few possess a depot facility to maintain a therapeutic dosage in the cochlea, avoiding its clearance mechanisms. To satisfy the potential need for delivery of such substances uniformly over a substantial length of the cochlea, the concept of delivery from an integral gel or fluid-filled reservoir in the body of the electrode array has been investigated both in vitro and in vivo. The concept involves a single, wide channel extending most of the length of the electrode array and (potentially) beyond the intracochlear portion by several centimetres (fig.
28] demonstrated considerable efficacy of AM111 against hearing loss caused by inflammation. Both drugs therefore appear viable for further development. The suitability of a drug for use in the inner ear depends on many factors. Foremost is the issue of safety. Additionally, specific features of the drug and its formulation are important to the design of the delivery system . These include molecular weight and charge, rate of clearance, time of action, adherence to the materials of the system, stability, specificity, and solubility.
The success of the electric acoustic stimulation approach demonstrates that partial blockage of the round window by a foreign body does not significantly suppress cochlear 30 5 10 15 20 25 Insertion depth (mm) mechanics. This fact has also been recently demonstrated by the successful placement of an implantable middle ear mechanical transducer in the round window niche . With the round window approach, the point of 1st contact between the electrode tip and the lateral wall takes place sooner than with a cochleostomy approach.
Cochlear Implants and Hearing Preservation (Advances in Oto-Rhino-Laryngology, Vol. 67) by Paul Van de Heyning, Andrea Kleine Punte