By Y. Yoshihara (auth.), Sigrun Korsching, Wolfgang Meyerhof (eds.)
The feel of scent has diverse roles in finding nutrients, detecting predators, navigating, and speaking social info, while the flavor process is concentrated on decision-making in foodstuff consumption. the decade has witnessed monstrous advances in realizing the molecular common sense of chemosensory details processing, and the consequences for style sensation have been chanced on to vary in attention-grabbing methods from these for scent sensation. The 12 chapters of this publication disguise the present wisdom concerning the chemosensory platforms in mammalian, fish and bug versions. some great benefits of different version structures are emphasised. The genomic features and evolution of olfactory and gustatory receptor gene households are analyzed, ideas for odorant receptor gene selection and axonal projection of the corresponding receptor neurons are mentioned, and the similarities and dissimilarities of pheromone vs. odorant sensing are tested in addition to the molecular common sense of mammalian candy flavor, sour style, and fats conception. Olfactory-guided and taste-guided behaviors are mentioned, with a selected emphasis at the insect system.
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Extra resources for Chemosensory Systems in Mammals, Fishes, and Insects
As the assembly has been optimizing, we expected to see a few pseudogenes to be annotated as intact while the repertoire size are relatively similar. Results from different research groups also have small discrepancies because of using slightly variable filtering criteria or searching methods. Additionally the curated database that includes functions likely for particular genes is occasionally discovered to be inaccurate. These errors can propagate through the database, as a gene incorrectly identified by its initial discoverer is used as a model in data mining, and all similar sequences are classified as having a similar function.
1 Olfactory Receptor Repertoire The size of OR repertoire varies dramatically among different species, but the reasons for this are unknown. While many primates have a reduced repertoire of functional receptor genes, family size is not in general coordinated with the apparent dependence on olfaction in the species niche; for example dogs have many fewer than rats. Exhaustive data with updated genomes has revealed that humans have 851 olfactory receptors genes, but only 384 among them are functionally intact (Glusman et al.
It has been hypothesized that these features provide for efficient adaptation of the olfactory sense to changing environmental conditions. Several recent publications have established the respective properties of the corresponding fish Fig. 1 The four olfactory receptor gene families. ORs, ORAs, and TAARs belong to the class A of GPCRs, with a short N-terminus and a ligand binding site within the TM domains, whereas OlfCs are class C GPCRs, similar to the metabotropic glutamate receptor, with the ligand binding pocket in the large N-terminal extracellular domain The Molecular Evolution of Teleost Olfactory Receptor Gene Families 3 receptor gene families.
Chemosensory Systems in Mammals, Fishes, and Insects by Y. Yoshihara (auth.), Sigrun Korsching, Wolfgang Meyerhof (eds.)