By Gaetano Thiene M.D., Marialuisa Valente M.D. (auth.), Cristina Basso, Marialuisa Valente, Gaetano Thiene (eds.)
Cardiac tumors have been as soon as a nosographic entity of scarce scientific curiosity as a result rarity and of the intrinsic diagnostic and healing impossibilities, and have been thought of a deadly morbid entity. It has now turn into a topical topic because of advances in scientific imaging (echo, magnetic resonance, computed tomography) in addition to innovation in applied sciences of in-vivo prognosis. Cardiac Tumor Pathology offers a extraordinary instance of those advances with clinico-pathologic correlations. This well timed quantity covers background, epidemiology, demographics, scientific prognosis, pathology, imaging by means of echo, CT and MRI of either benign and malignant cardiac tumors, both fundamental or secondary. Chemotherapy of malignant neoplasms is additionally addressed. targeted emphasis is given to clinico-pathologic correlations. With all chapters written by way of specialists of their fields, this quantity will function an invaluable source for physicians facing, and attracted to, this certain department of cardiac oncology and should signify an invaluable advisor for pathologists, clinicians, cardiologists, cardiac surgeons, and radiologists in addition to for postgraduate scholars education in those areas.
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Extra resources for Cardiac Tumor Pathology
Myxoma often presents as a smooth, oval and lobulated, or villous, friable and soft or gelatinous-like mass (Fig. 1). Flat and sessile myxomas are rare, and might result from embolization of most tumor mass. Rarely, cardiac myxomas show extensive calcifications with stone-like consistency, the so-called lithomyxoma , which is usually asymptomatic although complete embolization has been reported after pedicle detachment with floatation into the aorta causing patient death . 35 Common features.
8/1, a mean age at diagnosis of 50 years, most patients being in 30–60 age range [5, 17]. , Carney complex) they are diagnosed in young patients without sex predilection [13, 21, 22]. C. Basso et al. 1007/978-1-62703-143-1_3, © Springer Science+Business Media New York 2013 31 G. Bartoloni and A. Pucci 32 Clinical Aspects The clinical features are determined by their location, size, and mobility, and there is no any pathognomonic sign or symptom [2, 14, 15]. The most common presenting symptom is systemic embolism (30–50% of cases) requiring histology for etiological diagnosis, followed by congestive heart failure because of mitral valve obstruction with possible supraventricular arrhythmias .
Cases 30 25 20 15 10 5 0 0-10 yrs 11-20 yrs 21-30 yrs 31-40 yrs 41-50 yrs 51-60 yrs 61-70 yrs >70 yrs Fig. 5 Cardiac myxoma, University of Padua Medical School (1970–2010): 141 bioptic cases. Distribution according to age intervals cally resected myxomas has been collected, representing 59% of all primary bioptic cardiac tumors and 66% of benign bioptic cardiac tumors. 5%), the age range was 2–85 years (mean 54 ± 16, median 56). 5 reports the distribution of cardiac myxomas per age, showing a peak of incidence in people 50–60 years of age; only six cases (4%) have been surgically resected in the pediatric age (<18 years).
Cardiac Tumor Pathology by Gaetano Thiene M.D., Marialuisa Valente M.D. (auth.), Cristina Basso, Marialuisa Valente, Gaetano Thiene (eds.)