By Rodney Reznek
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Additional resources for Cancer of the Ovary
Adult granulosa cell tumours are solid, white or tan, bossellated tumours with a smooth contour. A small percentage have cysts. The tumour may have extensive lipid accumulation and be yellow, corresponding with the capacity for these tumours to secrete steroid hormones, especially oestrogens (with the resulting effects on endometrium of hyperplasia and occasionally neoplasia). The tumour cells microscopically are generally uniform, partly diffuse and partly arranged in a microcystic, rosette pattern as Call-Exner bodies.
7 An atypically proliferating Brenner tumour composed of sheets of transitional cell epithelium surrounded by the specific Brenner stroma. also has some effect on prognosis: tumours of endocervical type appear to behave more indolently than those of intestinal type, though the numbers studied are small . Borderline Endometrioid Ovarian Neoplasia These are rare. They may arise from the surface epithelium of the ovary or from deposits of endometriosis. The tumours may be of mixed glandular and fibrous type (adenofibromatous), papillary or villoglandular, or mixed.
De Jong, et al. Analysis of tumor heterogeneity in a patient with synchronously occurring female genital tract malignancies by DNA flow cytometry, DNA fingerprinting and immunohistochemistry. Cancer (1988), 62:1146À52. 33. S. B. Lele, M. S. Piver, J. J. Barlow, et al. Squamous cell carcinoma arising in ovarian endometriosis. Gynecol Oncol (1978), 6:290À3. 34. R. H. Young, J. Prat and R. E. Scully. Ovarian endometrioid carcinomas resembling sex cord stromal tumours. A clinicopathological analysis of 13 cases.
Cancer of the Ovary by Rodney Reznek