Download e-book for kindle: Breast Pathology: A Volume in the Series: Foundations in by Frances P. Malley, Sarah E. Pinder, Anna Marie Mulliga

February 1, 2018 | Pathology | By admin | 0 Comments

By Frances P. Malley, Sarah E. Pinder, Anna Marie Mulliga

ISBN-10: 1437717578

ISBN-13: 9781437717570

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Additional resources for Breast Pathology: A Volume in the Series: Foundations in Diagnostic Pathology

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Surgery with segmental excision and oncoplastic partial breast reconstruction may be the best option in such cases. Autoimmune Mastitis Granulomatous mastitis is an uncommon condition, usually presenting in the third or fourth decade. The etiology is largely unknown, although it may be associated with hyperprolactinemia. Granulomatous mastitis may present as a suspicious breast lump, but classically the clinical picture is of multiple tender lumps forming sinuses at needle biopsy sites and discharging sterile pus.

This tumor shows predominantly strong reactivity in the majority of tumor cell nuclei. a previous needling procedure; such spindle cell proliferations can be problematic. Possible diagnoses include fibromatosis, nerve sheath tumor, myofibroblastoma, phyllodes tumor, metaplastic carcinoma, or even primary sarcoma. In an older patient, a high index of suspicion of metaplastic carcinoma is appropriate and a low threshold for resorting to immunohistochemistry is advised. As described in Chapter 18, a range of anticytokeratin antibodies is often required for recognition of the epithelial nature of these lesions and, if positive, a definitive diagnosis can be made.

Duct papillomas most frequently present as nipple discharge and are discussed later. However, larger papillomas occasionally present as a discrete hard lump beneath, or close to, the areola. In such cases, even if the preoperative needle core biopsy shows no evidence of malignancy, 29 CHAPTER 4 Overview of Clinical Aspects of Breast Disease fibrous, nontender thickenings. Once a diagnosis is made (by core biopsy), the condition is managed conservatively. Spontaneous regression may occur over a few years.

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Breast Pathology: A Volume in the Series: Foundations in Diagnostic Pathology by Frances P. Malley, Sarah E. Pinder, Anna Marie Mulliga


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