By Pei Hui, Natalia Buza (auth.)
This atlas is devoted particularly to gynecologic frozen part analysis and addresses specialist perform gaps reminiscent of excessive diagnostic blunders expense, sluggish turnaround time, and inefficient conversation among surgeons and pathologists on the time of intraoperative frozen part session of gynecologic specimens. The layout of the amount is a mixture of concise textual content and top of the range gross and frozen part microscopic photographs, meticulously chosen from the excellent choice of pathology specimens of gynecologic tumors supplied at Yale-New Haven health facility some time past a long time. widespread entities with diagnostic pitfalls are balanced with much less universal lesions. recommendations to acknowledge their diagnostic positive factors are emphasised, as well as the effect on optimum surgery of sufferers with gynecologic melanoma. the symptoms, boundaries, morphologic diagnostic standards and pitfalls of frozen part session in gynecologic pathology are completely reviewed with an final target of fending off sufferer mismanagement in real-time. top of the range frozen part microscopic illustrations relief the popularity of morphologic styles and function fast reference in the course of intraoperative session.
Written by means of specialists within the box, Atlas of Intraoperative Frozen part analysis in Gynecologic Pathology is a worthy source for pathologists in any respect career/expertise degrees who're interested in intraoperative session of their day-by-day scientific perform.
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Additional info for Atlas of Intraoperative Frozen Section Diagnosis in Gynecologic Pathology
Firm indurated mass leading to barrel-shaped cervix. • Deep invasion of haphazardly distributed open glands of highly variable sizes and unusual shapes is characteristic (Fig. 17). • Tumor cells contain abundant mucin with basally located nuclei. • Unequivocal dysplastic glands and/or single or clusters of infiltrating tumor cells with stromal response (Fig. 18). • Close juxtaposition of glands to large caliber vessels, involvement of lower uterine segment myometrium or parametrium, and presence of lymphovascular or perineural invasion.
3 Deep nabothian cyst. Deeply seated, cystically dilated endocervical glands filled with mucin (a, b) Tumorlike Conditions of the Cervix 31 Lobular and Diffuse Laminar Endocervical Glandular Hyperplasia [2, 3] • Benign mucinous glandular proliferations, in a lobular or diffuse laminar pattern. • May be deeply seated lobular mass lesions involving cervical stroma, exceeding 1 cm in size (Fig. 4). • Both types show crowded hyperplastic glands lined by mucin-producing endocervical glandular epithelial cells.
Histologically the tumor resembles conventional breast ductal and lobular carcinomas. • At the time of frozen section diagnosis, metastasis from a breast primary must be ruled out before such diagnosis is made. b Fig. 13 Vulvar Paget disease. Note the red eczematous plaques involving labia majora and minora (multiple sections have been taken for frozen section evaluation of margin involvement) (a, b) 18 2 a b c d Vulva and Vagina Fig. 14 Vulvar Paget disease. Note singles and clusters of large round mucin-containing cells involving the lower half and focally the entire squamous epithelium (a–c) with subtle glandular structure formation (d) Mesenchymal Tumors Mesenchymal Tumors Although rare, a variety of benign and malignant soft tissue tumors may occur in the vulva and vagina.
Atlas of Intraoperative Frozen Section Diagnosis in Gynecologic Pathology by Pei Hui, Natalia Buza (auth.)