Download PDF by Irving J. Selikoff (Auth.): Asbestos and Disease

February 1, 2018 | Pathology | By admin | 0 Comments

By Irving J. Selikoff (Auth.)

ISBN-10: 0126360502

ISBN-13: 9780126360509

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For five years he had noticed some shortness of breath, and his complaint on admission was pain in the right side of the " s t o m a c h / ' He was autopsied on March 17, 1934. An epidermoid carcinoma of the right lung was found, and extensive fibrosis and asbestosis were also seen. The authors did no more than draw attention to the simultaneous presence of the two diseases. In October of the same year Gloyne published two cases from Britain, both in women (279). One had eight years of exposure as a spinner nine years before, the other only 19 months in the mattress and opening departments, 15 years before.

Histologically, the peritoneum showed exuberant proliferation and intense swelling of the mesothelial cells, and other cytological findings were consistent with what we now recognize as mesothelioma. Leichner reported finding evidence of asbestos fibers in the tumor. Bonser, Faulds, and Stewart reported four primary peritoneal tumors associated with asbestosis in 1955 (101). In 1958, Van der Schoot reported on three insulation workers who had died of neoplasms, two of them apparently mesotheliomas of the pleura; Schornagel mentioned a case in the discussion that he had seen of peritoneal mesothelioma (756).

In general, the amphiboles are less affected by acids than is chrysotile; with crocidolite, tremolite and anthophyllite the most resistant (Table 2 - 3 ) . Amosite and actinolite apparently show an intermediate reactivity. 80 a With kind permission of S. Speil. Amosite and actinolite are also somewhat susceptible to the action of strong alkalies, but the remaining asbestiform materials are resistant. The resistance of asbestos to reagents other than acids is good up to 100°C, but decreases rapidly at higher temperatures.

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Asbestos and Disease by Irving J. Selikoff (Auth.)


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