Read e-book online Anthracycline Antibiotics. New Analogues, Methods of PDF

February 1, 2018 | Oncology | By admin | 0 Comments

By Waldemar Priebe

ISBN-10: 0841214956

ISBN-13: 9780841214958

ISBN-10: 0841230404

ISBN-13: 9780841230408

content material: Unresolved structure-activity relationships in anthracycline analogue improvement / Edward M. Acton --
Non-cross-resistant anthracyclines with lowered basicity and elevated balance of the glycosidic bond / Waldemar Priebe, Piotr Skibicki, Oscar Varela, Nouri Neamati, Marcos Sznaidman, Krzysztof Dziewiszek, Grzegorz Grynkiewicz, Derek Horton, Yiyu Zou, Yi-He Ling, and Roman Perez-Soler --
Fluorinated anthracyclinones and their glycosylated items / Antonio Guidi, Franca Canfarini, Alessandro Giolitti, Franco Pasqui, Vittorio Pestellini, and Federico Arcamone --
Semisynthetic rhodomycins and anthracycline prodrugs / Cenek Kolar, Klaus Bosslet, Jörg Czech, Manfred Gerken, Peter Hermentin, Dieter Hoffmann, and Hans-Harold Sedlacek --
artificial strategies for reversal of anthracycline resistance and cardiotoxicity / Claude Monneret, Jean-Claude Florent, Jean-Pierre Gesson, Jean-Claude Jacquesy, François Tillequin, and Michel Koch --
Synthesis and organic actions of fluorinated daunorubicin and doxorubicin analogues / Tsutomu Tsuchiya and Yasushi Takagi --
Redox chemistry of anthracyclines and use of oxomorpholinyl radicals / Tad H. Koch and Giorgio Gaudiano --
Synthesis of anthraquinone analogues of associated anthracycline / Ping Ge and Richard A. Russell --
Synthesis and research of structure-activity relationships of latest periods of anthracyclines / Antonino Suarato, Francesco Angelucci, Alberto Bargiotti, Michele Caruso, Daniela Faiardi, Laura Capolongo, Cristina Geroni, Marina Ripamonti, and Maria Grandi --
Molecular attractiveness of DNA via daunorubicin / Jonathan B. Chaires --
Adducts of DNA and anthracycline antibiotics : constructions, interactions, and actions / Jasmine Y.-T. Wang, Mark Chao, and Andrew H.-J. Wang --
DNA topoisomerases and their inhibition by way of anthracyclines / Yves Pommier --
Anthracycline antihelicase motion : new mechanism with implications for guanosine-cytidine intercalation specificity / Nicholas R. Bachur, Robin Johnson, Fang Yu, Robert Hickey, and Linda Malkas --
Membrane biophysical parameters influencing anthracycline motion / Ratna Mehta and Thomas G. Burke --
sign transduction platforms in doxorubicin hydrochloride mechanism of motion / Paul Vichi, James track, Jean Hess, and Thomas R. Tritton --
research of multidrug transporter in residing cells : software to uptake and unlock of anthracycline derivatives by means of drug-resistant K562 cells / Arlette Garnier-Suillerot, Frédéric Frézard, Marie-Nicole Borrel, Elene Pereira, Jolanta Tarasiuk, and Marina Fiallo --
function of reactive-oxygen metabolism in cardiac toxicity of anthracycline antibiotics / James H. Doroshow --
Amelioration of anthracycline-induced cardiotoxicity through natural chemical compounds / Donald T. Witiak and Eugene H. Herman --
Use of drug vendors to ameliorate the healing index of anthracycline antibiotics / Roman Perez-Soler, Steven Sugarman, Yiyu Zou, and Waldemar Priebe.

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Extra resources for Anthracycline Antibiotics. New Analogues, Methods of Delivery, and Mechanisms of Action

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ACS Symposium Series; American Chemical Society: Washington, DC, 1994. 2. PRIEBEETAL. Non-Cross-Resistant Anthracyclines 29 leukemia (T/C 196 at 25 mg/kg) and Lewis lung carcinoma (T/C 187 at 25 mg/kg), and significant activity against B-16 melanoma (T/C 218 at 25 mg/kg). Compound 35 in a tab configuration was less efficacious than 37 and had activity comparable with daunorubicin ( T / C 162), but was significantly less potent. The β-L-g/wco analogue 38 did not display activity up to the highest tested dose of 50 mg/kg.

In Anthracycline Antibiotics; El Khadem, H . : New York, 1982, p. 197. ; Zamojski, A. Tetrahedron 1980, 36, 287. ; Neamati, N . ; Perez-Soler, R. Tetrahedron Lett. 1991, 32, 3313. ; Priebe, W. Proc. Am. Chem. Soc. , CARB-22, San Francisco, 1980. ; Priebe, W. Proc. Am. Chem. Soc. , CARB-11, New York, 1981. ; Varela, O. Abstr. Pap. XIth Internat. Carbohydr. Symp. Vancouver, 1982. Naff, M . ; Narayanan, V. , In Anthracycline Antibiotics; El Khadem, H . ; Academic Press, Inc: New York, 1982, p. 1.

Symp. B-64, Stockholm, 1988. ; ACS Symposium Series; American Chemical Society: Washington, DC, 1994. 2. PRIEBE 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. ET AL. ; Neamati, N . ; Perez-Soler, R. J. Antibiot. 1990, 43, 838. ; Priebe, W. Cancer Chemother. Pharmacol. 1992, 30, 267. ; Pommier, Y. Int. J. Cancer, 1994, 58, 85-94. Chaires, J. ; Graves, D. ; Burke, T. G. J. Am. Chem. Soc. 1993, 115, 5360. Friedman, R. A. ; Manning, G. Biopolymers 1984, 23, 2671.

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Anthracycline Antibiotics. New Analogues, Methods of Delivery, and Mechanisms of Action by Waldemar Priebe


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